Expression of Interest

Contact Person/Scientist in Charge

  • Name and surname: L. Gonzalo de la Casa
  • Email: ogpiSPAMFILTER@us.es

Oficina General de Proyectos Internacionales Universidad de Sevilla

Department / Institute / Centre

  • Name: Department of Experimental Psychology - University of Seville
  • Address: C/ Camilo José Cela, s/n, 41018 Sevilla (Spain)
  • Province: Sevilla

Research Area

  • Social Sciences and Humanities (SOC)

Brief description of the institution:

The Universidad de Sevilla (US) was established in 1505 and, with more than 70000 students and 6700 staff, is the third largest university in Spain. US embraces academia, industry, engineering and science and, with a relevant educational and technological infrastructure, is an intellectual reference in the South of Europe.

More than 10000 students are following postgraduate courses, enrolled into 86 master programs and 152 doctoral programs. And the university holds academic partnerships with 850 institutions throughout the world.

US is also devoted to research and innovation; therefore, in addition to its 4300 academic staff, there are 1600 researchers and over 470 scientific groups associated to the university. Research is carried out within academic departments, in 6 research centers and 9 university research institutes.

Research facilities offer highly advanced research services at the Center for Research, Technology and Innovation (CITIUS) that provides the most advanced and state-of-the-art analytical instrumentation and techniques to research groups, public research institutes and industries This is complemented by important national research centers such as the Institute in Mathematic Research (IMUS), the Biomedicine Research Institute (IBIS), the National Research Center for Accelerators (AMS) and the Institute of Microelectronics (IMSE-CNM).

The researchers with Marie Curie contracts at US will be considered for tenure track at the end of their contract.

Brief description of the Centre/Research Group (including URL if applicable):

Research in the Laboratory of Animal Behavior and Neuroscience of Seville University (Spain) is focused on the analysis of classical conditioning and its neural basis, both with animals and humans. We promote experimental research and encourage creativity and critical thinking in our researchers. URL: http://alojamientos.us.es/conductaanimal/

Project description:

Our main interest is focused in the analysis of the possible associations between contextual cues and those responses induced by agonists or antagonists of the dopamine system. Our hypothesis, based on previous data from the literature and in preliminary studies conducted in our laboratory, anticipates that the repeated administration of dopaminergic drugs in the presence of a specific context will result in the establishment of an association between the context and the effect of the drug. Such association will induce a conditioned response to the context similar to that produced by the drug administration. To test our hypothesis we are conducting several experimental series with animals (Wistar rats) and human participants (schizophrenic patients and participants without pathologies) with the following objectives: 1) to analyze whether repeated administration of dopamine agonists or antagonists in presence of a context turns such context into a conditioned stimulus capable of modulate behavioral phenomena that depends on dopaminergic activity; 2) to check whether the presentation of the context associated with the drug induces changes in dopaminergic activity using cerebral microdyalisis techniques; 3) to check whether the results we expect to obtain in animal research related to contextual conditioning of dopaminergic responses can be generalized to human participants with or without pathologies. As an additional objective we are interested in exploring in additional experiments with animals if the associations between the context and the effects of dopaminergic drugs can also be observed with drugs that affect to glutamatergic activity.

Applications

Detailed CV, motivation letter, two recommendation letters

I want to contact the Institution

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